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People who have better aerobic fitness in middle age may ward off decreases in brain volume later in life, potentially preserving memory and other functions, a U.S. study suggests.

“The current findings suggest that maintaining high fitness in midlife may boost brain health on average 20 years later in adults who have not yet experienced cognitive impairment,” lead study author Qu Tian, a gerontology researcher at the U.S. National Institute on Aging, said by email.

Tian and colleagues followed 146 older adults over a decade, using treadmill tests to measure cardiorespiratory fitness. They also used magnetic resonance imaging (MRI) to detect changes in brain volume.

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